Shadowrun's Harlequin's Back

There used to be some Shadowrun players hanging around here. Maybe not
many, but this question has elements that is open to those who never
looked at the game.

In the perhaps near future I'll be running the Harlequin's Back module
for my group. I've already had to make any number of serious changes
to it to fit it in with my own 're-imagined' Shadowrun setting.

One of which is booting Harlequin himself :)

In any case, the module itself is rather typical. Good basic idea with
so-so execution. The basic concept is a quest through the metaplanes
to assemble a defense of Earth from an invading horde. Sort of close
off the hot gates instead of holding them.

The metaplanes can be just about anything, each it's own self-
contained world. The module uses steam-punk wild west and gothic
mystery as a couple of examples. Others are less... interesting.

In any case, I'm looking for suggestions for what to swap in for some
settings I'm going to swap out. Plus would like to hear from anyone
who ran the module before- what worked and what didn't stuff.